Mediterranean fever...
(Family Mediterranean fever)
This disease occurs in which repeated episodes of fever (high temperature), associated with the occurrence of infections in the membranes surrounding the organs, such as:
The peritoneum is in the abdomen, and the pain is similar to surgical inflammation to the extent that there are some patients who have not been diagnosed surgically opened on suspicion of appendicitis, or others in the abdomen,
Abdominal symptoms are the most common and frequent among patients with this disease.
Among the membranes: the crystalline membrane surrounding the lung, and severe chest pain often occurs on one side, it takes a few days and gradually subsides, and there is pain with the movement of the rib cage if the patient breathes deeply, coughs or laughs strongly.
Among the membranes also: the membranes surrounding the joints, and inflammation of the major joints often occurs, such as: the knee, ankle and wrist joints, and the inflammation takes several days, and the joints between attacks are completely intact.
There are some cases in which a rash occurs, often below the knee, and is associated with the presence of fever.
There is a smaller percentage of cases with symptoms associated with muscle pain, and cases with symptoms of pelvic inflammation.
The causes of this disease are genetic, and the gene associated with the presence of this disease has been identified, and it is located in the short arm of chromosome number 16,
It is common in the Mediterranean, and is a recessive gene; That is, the mother and the father carry one copy of the gene.
The infection occurs in children in 25% of each pregnancy when there is a chance that one of the children will carry two copies of the gene and develop the disease.
The diagnosis of this disease is certain:
1. Genetic analysis is performed to ensure the presence of the disease-causing gene,
2. The diagnosis can be made by recurring attacks, which last at most three days and disappear even without treatment
3. Or the rise of some substances associated with acute inflammation, especially amyloid deposits, which are elevated in cases infected with this disease and are associated with recurrent inflammatory attacks.
The only effective treatment for cases of this disease is:
.... Colchicine ..... One tablet daily
......... and between attacks, a tablet in the morning and evening
It is taken on a daily basis, and daily regularity is recommended to avoid and reduce exposure to inflammatory attacks, and to reduce the chance of any complications.
The complications associated with this disease are due to the deposition of amyloid in the kidneys, and the occurrence of kidney failure,
This only happens with repeated episodes of inflammation without proper treatment.
However, this can be avoided with regular treatment.
In the event of kidney failure, the condition must be carefully monitored, and the treatment with colchicine should be regular.
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Mediterranean fever...
(Family Mediterranean fever)
This malady happens during which continual episodes of fever (high temperature), related to the prevalence of infections within the membranes close the organs, such as:
The serous membrane is within the abdomen, and therefore the pain is comparable to surgical inflammation to the extent that there square measure some patients World Health Organization haven't been diagnosed surgically opened on suspicion of rubor, or others within the abdomen,
Abdominal symptoms square measure the foremost common and frequent among patients with this malady.
Among the membranes: the crystalline membrane close the respiratory organ, and severe hurting typically happens on one aspect, it takes some days and bit by bit subsides, and there's pain with the movement of the skeletal structure if the patient breathes deeply, coughs or laughs powerfully.
Among the membranes also: the membranes close the joints, and inflammation of the most important joints typically happens, such as: the knee, ankle joint and carpus joints, and therefore the inflammation takes many days, and therefore the joints between attacks square measure utterly intact.
There square measure some cases during which a rash happens, typically below the knee, and is related to the presence of fever.
there's a smaller share of cases with symptoms related to muscle pain, and cases with symptoms of girdle inflammation.
The causes of this malady square measure genetic, and therefore the cistron related to the presence of this malady has been known, and it's situated within the short arm of body variety sixteen,
it's common within the Mediterranean, and could be a recessive gene; that's, the mother and therefore the father carry one copy of the cistron.
The infection happens in youngsters in twenty fifth of every gestation once there's an opportunity that one in every of the kids can carry 2 copies of the cistron and develop the malady.
The designation of this malady is certain:
1. Genetic analysis is performed to confirm the presence of the disease-causing cistron,
2. The designation may be created by revenant attacks, that last at the most 3 days and disappear even while not treatment
3. Or the increase of some substances related to acute inflammation, particularly amyloid deposits, that square measure elevated in cases infected with this malady and square measure related to repeated inflammatory attacks.
the sole effective treatment for cases of this malady is:
.... Colchicine ..... One pill daily
......... and between attacks, a pill within the morning and evening
it's taken on a day to day, and daily regularity is usually recommended to avoid and scale back exposure to inflammatory attacks, and to scale back the prospect of any complications.
The complications related to this malady square measure because of the deposition of amyloid within the kidneys, and therefore the prevalence of kidney disease,
This solely happens with continual episodes of inflammation while not correct treatment.
However, this could be avoided with regular treatment.
within the event of kidney disease, the condition should be rigorously monitored, and therefore the treatment with colchicine ought to be regular.
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